Health news
The Food and Drug Administration (FDA) has granted Fast Track status to the combination of ervogastat and clesacostat for the treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. Ervogastat is a diacylglycerol O-acyltransferase 2 inhibitor…
Ibsrela® (tenapanor) is now available for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults. Ibsrela is a locally-acting inhibitor of the sodium/hydrogen exchanger 3 (NHE3), an antiporter expressed on the apical surface…
Edenbridge announced the availability of Dartisla ODT, an orally disintegrating tablet formulation of glycopyrrolate, to reduce symptoms of a peptic ulcer as an adjunct to treatment of peptic ulcer. Dartisla ODT received approval from the…
The Food and Drug Administration (FDA) has granted Fast Track designation to AXA1125 for the treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. AXA1125 is an orally active mixture of amino acids (endogenous metabolic modulator…
The Food and Drug Administration (FDA) has granted Fast Track designation to CRV431 for the treatment of nonalcoholic steatohepatitis (NASH). CRV431 works by specifically binding to cyclophilin isomerase enzymes and inhibiting cyclophilin function with high…
AbbVie has submitted a regulatory application to the Food and Drug Administration for risankizumab-rzaa for the treatment of patients 16 years of age and older with moderate to severe Crohn disease. The application is supported…
Pharmacotherapies used in the treatment of nonalcoholic steatohepatitis (NASH) were compared in a recent systematic review and network meta-analysis published in Alimentary Pharmacology & Therapeutics. Although NASH is a common cause of chronic liver disease,…
The Food and Drug Administration has approved Livmarli (maralixibat) oral solution for the treatment of cholestatic pruritus in patients with Alagille syndrome 1 year of age and older. Livmarli is a reversible inhibitor of the…
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