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The Food and Drug Administration (FDA) has accepted for Priority Review the supplemental Biologics License Application (sBLA) for the use of pegloticase injection plus methotrexate for the treatment of uncontrolled gout. Pegloticase, a PEGylated uric…
Four healthy diets were linked to gout prevention in women enrolled in the Nurses’ Health Study: the Dietary Approaches to Stop Hypertension (DASH), Mediterranean, Alternative Healthy Eating Index (AHEI), and Prudent diets. The DASH diet…
Intensive oral urate-lowering therapy (ULT) does not improve bone erosion scores and leads to a higher medication burden in patients with erosive gout, according to results of a randomized double-blind controlled study published in Arthritis…
A supplemental Biologics License Application (sBLA) has been submitted to the Food and Drug Administration (FDA) for pegloticase injection plus methotrexate for the treatment of uncontrolled gout. Pegloticase is currently marketed under the brand name…
The Food and Drug Administration (FDA) has granted Fast Track designation to ALLN-346 for the treatment of hyperuricemia in gout patients with advanced chronic kidney disease. ALLN-346 is an investigational, first-in-class, nonabsorbed, orally-administered enzyme that…
Compared with healthy individuals, patients with gout were found to have a significantly unique gut microbiota associated with dysregulated host urate degradation and systemic inflammation, according to study results published in NPJ Biofilms and Microbiomes.…
September 2021 has been declared as both Pain Awareness and Arthritis Awareness Month. An estimated 20% of Americans have chronic pain, with 8.0% of US adults experiencing high-impact chronic pain.1 Gout, one of the most…
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