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Supernus One Step Closer to Decision on Apomorphine Infusion Device > Parkinson Disease

Category: Parkinson Disease

Supernus One Step Closer to Decision on Apomorphine Infusion Device
General General Neurology Neurologic Disorders News Parkinson Disease

Supernus One Step Closer to Decision on Apomorphine Infusion Device

Steve Duffy February 22, 2022

The Food and Drug Administration (FDA) has assigned a Prescription Drug User Fee Act (PDUFA) target date for SPN-830, an apomorphine infusion device for the continuous treatment of motor fluctuations (off episodes) in adults with…

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Amyotrophic Lateral Sclerosis Prevention: Neurodegenerative Diseases Offer Insight

Top-Meds December 29, 2021

Lessons learned from various presymptomatic neurodegenerative diseases may provide opportunities for early intervention, and perhaps even disease prevention of amyotrophic lateral sclerosis (ALS), according to a review published in the journal Brain. Studies have shown…

Novel Pramipexole-Rasagiline Combo Promising for Early Parkinson Disease

Steve Duffy December 16, 2021

A phase 3 study evaluating a novel fixed-dose combination of extended release (ER) formulations of pramipexole and rasagiline (P2B001) in adults with early Parkinson disease met its primary and key secondary endpoints. The 12-week, multinational,…

Treating Motor Symptoms in Early Parkinson Disease: AAN Releases New Guidelines

Top-Meds December 2, 2021

The American Academy of Neurology (AAN) released updated guidelines on the initiation of dopaminergic therapy for the treatment of motor symptoms in patients with early Parkinson disease (PD). A summary of these guidelines was published…

AAN Updates Recommendations for Early Parkinson Disease Treatment

Steve Duffy November 16, 2021

The American Academy of Neurology (AAN) has issued updated guidelines on initiating dopaminergic therapy for motor symptoms in early Parkinson disease. According to the guidelines, counseling should be provided to individuals with early Parkinson disease…

Focused Ultrasound Device Approved for Advanced Parkinson Disease
Devices General Neurologic Disorders News Parkinson Disease

Focused Ultrasound Device Approved for Advanced Parkinson Disease

Top-Meds November 3, 2021

The Food and Drug Administration (FDA) has expanded the approval of Exablate® Neuro to include treatment of medication-refractory Parkinson disease patients with moderate to severe motor complications. Using MRI-guided focused ultrasound, the device is able…

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Continuous SC Infusion Therapy Bests Oral Levodopa/Carbidopa in Parkinson Trial
General Neurologic Disorders News Parkinson Disease

Continuous SC Infusion Therapy Bests Oral Levodopa/Carbidopa in Parkinson Trial

MPR October 29, 2021

Positive results were announced from a phase 3 study evaluating the efficacy and safety of ABBV-951 (foslevodopa/foscarbidopa) in patients with advanced Parkinson disease. ABBV-951 is a solution of levodopa and carbidopa prodrugs for continuous subcutaneous…

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Inosine Fails to Slow Early Parkinson Disease Progression in Phase 3 Trial
General Movement Disorders News Parkinson Disease

Inosine Fails to Slow Early Parkinson Disease Progression in Phase 3 Trial

Neurology Advisor October 18, 2021

Urate-elevating inosine treatment had no beneficial effect on the rate of clinical disease progression among patients with newly diagnosed Parkinson disease (PD), according to study results published in JAMA. Prior studies have suggested that urate,…

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Boxing Therapy May Reduce Risk for Falls in Patients With Parkinson Disease
COVID19 Emerging Diseases General Movement Disorders News Parkinson Disease

Boxing Therapy May Reduce Risk for Falls in Patients With Parkinson Disease

Neurology Advisor September 16, 2021

Boxing therapy may improve gait stability and reduce the risk for falls in patients with Parkinson disease (PD), according to study findings published in BMC Neurology. Motor impairment and gait instability in PD can increase…

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Neurodegenerative Disease and COVID-19: Assessing Outcomes in Hospitalized Patients
COVID19 Dementia General General Infectious Disease Neurodegenerative Diseases News Parkinson Disease

Neurodegenerative Disease and COVID-19: Assessing Outcomes in Hospitalized Patients

Neurology Advisor June 23, 2021

Short-term mortality and intensive care unit (ICU) admission rates among patients with neurodegenerative disorders who are hospitalized with COVID-19 may not differ from age-matched hospitalized patients with COVID-19 who do not have neurological disorders, according…

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