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The Food and Drug Administration (FDA) has assigned a Prescription Drug User Fee Act (PDUFA) target date for SPN-830, an apomorphine infusion device for the continuous treatment of motor fluctuations (off episodes) in adults with…
Lessons learned from various presymptomatic neurodegenerative diseases may provide opportunities for early intervention, and perhaps even disease prevention of amyotrophic lateral sclerosis (ALS), according to a review published in the journal Brain. Studies have shown…
A phase 3 study evaluating a novel fixed-dose combination of extended release (ER) formulations of pramipexole and rasagiline (P2B001) in adults with early Parkinson disease met its primary and key secondary endpoints. The 12-week, multinational,…
The American Academy of Neurology (AAN) released updated guidelines on the initiation of dopaminergic therapy for the treatment of motor symptoms in patients with early Parkinson disease (PD). A summary of these guidelines was published…
The American Academy of Neurology (AAN) has issued updated guidelines on initiating dopaminergic therapy for motor symptoms in early Parkinson disease. According to the guidelines, counseling should be provided to individuals with early Parkinson disease…
The Food and Drug Administration (FDA) has expanded the approval of Exablate® Neuro to include treatment of medication-refractory Parkinson disease patients with moderate to severe motor complications. Using MRI-guided focused ultrasound, the device is able…
Positive results were announced from a phase 3 study evaluating the efficacy and safety of ABBV-951 (foslevodopa/foscarbidopa) in patients with advanced Parkinson disease. ABBV-951 is a solution of levodopa and carbidopa prodrugs for continuous subcutaneous…
Urate-elevating inosine treatment had no beneficial effect on the rate of clinical disease progression among patients with newly diagnosed Parkinson disease (PD), according to study results published in JAMA. Prior studies have suggested that urate,…
Boxing therapy may improve gait stability and reduce the risk for falls in patients with Parkinson disease (PD), according to study findings published in BMC Neurology. Motor impairment and gait instability in PD can increase…
Short-term mortality and intensive care unit (ICU) admission rates among patients with neurodegenerative disorders who are hospitalized with COVID-19 may not differ from age-matched hospitalized patients with COVID-19 who do not have neurological disorders, according…
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